Document Type : Research Paper

Author

University of Salahaddin -College of Science

10.37652/juaps.2009.15554

Abstract

A simple rapid and accurate flow injection inhibitory chemiluminescence method has been developed for the determination of adrenaline hydrochloride based on its inhibition of the chemiluminescence from the luminol ،V potassium hexacyanoferrate (III) system. The linear range of determination is 8.0 „e 10-12 ،V 8.0 „e 10-10 mgl-1 for adrenaline hydrochloride and the detection limit is 4.0 „e 10-9 g ml-1. The method has been applied to determine the content of adrenaline in pharmaceutical preparation with satisfactory results.

Keywords

Main Subjects

1- D. Amin, Analyst, 1986, 111, 255.
2- M. Q. Al-Abachi and M.A. Al-Da’amy, National J. of chemistry, 2004, Volume 13, 47-56.
3- P. Nagaraja, R.A. Vasanthra and K.R. Sunitha, Talanta 2001, 55(6), 1039-1046.
4- F.A. Nour El-Dien, M.A.Zayed, Gehad G. Mohamed and Reham G. EL-Nahas J. of Biomedicine and Biotechnology, 2005, 1-9.
5- Y. Shen and M.Y.Ye, J. Liq. Chromotogr., 1994, 17, 1557.
6- H. M. Zhang, N. Q Li and Z.W. Zhu, Microchem. J., 2000, 64, 277.
7- N.T. Deftereos, A.C. Calokerinos and C.E. Efstathiou, Analyst, 1993, 118, 627.
8- Editorial committee of the Ministry of Health of P.R. china, “Pharmacopeia of P.R. China Part 2”, 1995, Chemical Industry Press, Beijing, 609.