Document Type : Research Paper

Author

college education altaarmih university Iraqi

Abstract

The histopathological effects 0f Staphylococcus xylosus supernatant killed by radiation on four organs (kidney, spleen, lung and liver) of mice injected with (104, 108) CFU/ ml were studied. The results showed that the bacteria induced histopathological effects in all organs. In kidney the effects characterized by cytoplasmic vacculation and infiltration of inflammatory cells in addition to congestion and shrinkage of the glomeruli of the kidney,while effects in spleen characterized by enlargement of white pulp and necrosis in parenchymal tissue with formation of germinal center.Liver section showed cytoplasmic vaculation and infiltration of inflammatory cells.

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Main Subjects

1] Kuboskova, D. (2004). Characterisation of Staphylococcus xylosus strains isolated from humans    clinical material. 14th ed .ECSMID. P.1680.
[2] Miller,W.R.;Pannell,L.; Cravitz,L.; Tanner,W.A.and Rosebury,T.1948. Studies  on certain biological characteristics of Malleomyces mallei and Malleomyce spseudomallei II. Virulence and infectivity for animals.J.Bacteriol.55:127 –  135.
[3].Fritz,D.L.;Vogel,P.;Brown,D.R.;Deshazer,D.andWaag,D.M.2000.Mouse  model of sublethal and lethal intraperitoneal glanders (Burkholderia  mallei).Vet.Pathol.37:626–636.
[4]. Tawfiq, H.K. (2007). Comparative pathogenicity of peptidoglycan extracted from Staphylococcus xylorus and standard lipopolysaccharide extract from E.coli.M.Sc. Thesis. University of Baghdad / Baghdad Iraq / College of Science.
[5]. Flayyih,  M.T.;  Kahdum,B.A.  and  Radeef,H.M.  2009.Isolation  of Bur k holder ia   ma llei  from  patients  with  wound  infection  and  study  their virulence . Al-Kufa University  J. Biology.  1(1):  467-475.
[6]. Collee,J.G.;  Fraser,A.G.;  Mormion,B.P.and  Simmons,A.1996.Mackie  &MacCartney  Practical  Medical  Microbiology.14thed.  Churchil  Livingstone, Neuyork.
[7]. Weijer , S .;    Sewnath,  M.E.;  DeVos,  A.F.;   F lorquin, S.; Gouma,   D. J. &   Takeda.(2003)Interleukin  -18 facilites the early antimicrobial host respons to  E.coli peritonitis.Infect.Immun.71:5488 -5497.
[8]. الکبیسی،    (2009) دلیل الطالب فی علم الانسجة (النظری والعملی).الطبعة الاولى ص 11-14.دار صفاء للنشر والتوزیع ،عمان ، الاردن.  [9].Humason, G.1972.Animal Tissue Technique.3rd. W.H.Freeman Company,  San Francisco.p:641.
[10]. Roelofs, J.  J. ; Rouschop, K. M.; Leemans, J. C.; Claessen, N.; Frederiks, W. M. & Florquin, S.(2006).Tissue-type plasminogen activator modulates renal function in ischemia reperfusion injury.J.Am.Soc.Nephrol. 17:131-140.
 [11]. Al-Ghrairy , Z.K.A. (2007). Comparative study on some pathological aspect between Staphylococcus xylosus and Staphylococcus saprophyticus. M.Sc. Thesis. University of Baghdad / Baghdad Iraq / College of Science.
 [12]. Thewaini , G. N. & Jabuk , S.I.(2010)  The study of pathogenicity determinant of enteropathogenic Ecoli isolated from infant with acute diarrhea. CSASC Ar. V. Vol.5 PP.260-269.Biology department.Babylon university.Iraq.
[13]. Ulrich,R.L.and Deshazer,D. 2004.Type IIIsecrection : a virulence factor  delivery system essential for the pathogenicity of Burkholderia mallei.  Infect.Immun. 72 (2): 1150 – 1154.
[14].Larsen,J.C.andJohnson,N.H.2009.PathogenesisofBurkholderia  pseudomallei and Burkholderia mallei. Mil. Med. 174(6):647-51.
[15].Cheng,A.C.andCurrie,B.J.2005.Melioidosis:epidemiology,  pathophysiology, and management. Clin. Microbiol. Rev.18:383–416.
[16]. Tseng, C. C.; Wu, J. J.; Liu, H. L.; Sung, J. M. &Huang, J. J. (2002).Rols of host and bacterial virulence factors in the development of upper urinary tract infection caused by E.coli.Am. J. Kidney Dis. 39:744-752.
[17] Valle, J.; Vadillo, S.; Pirizi, S. and Gomez-Lucia, E. (1991). Toxic shock syndrome toxin-1 (TSST-1) production by Staphylococci  isolated from goats and presence of specific antibodies to TSST-1 in serum and milk. J. Appl. Environ. Microbiol. 57(3): 889-891.
[18] Zhang, S. and Madox, C.W. (2000). Cytotoxic activity of coagulase-negative Staphylococci in bovine mastitis. Infect. And Immun. 68(3): 1102-1108.