Document Type : Research Paper
Authors
1 University of Anbar - College of Science
2 Erbil Polytechnic University - Erbil Medical Institute
Abstract
Gum was extracted from linseed (Linum usitissimum) in north of Iraq, which it annual growth plant. Organoleptic characterization of: color, odor, taste, fracture and texture. Physico-chemical properties were determined: pH, bulk density, tapped density, bulkiness, swelling index, ash values, carr's index, Hausner's ratio and angle of repose. Thin Layer Chromatography paper was used to monitor the extracted saccharides by comparing the spots with the of the standards and flow rate Rf calculated. The FT-IR spectrum of the product showed an absorption bands at 3666.29 cm-1(–OH), 2966.76 cm-1(C-H), 2640.44 cm-1 (C=C), 1826.62 (C=O), 1420.04 (C-H bend). Anti-microbial activity evaluated of the gum and observed that gum does not any significant antibacterial activity such as cell wall destruction.
Keywords
Main Subjects
- Allen L.V., Popovich N.G. and Ansel H.C., (2010) Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems, 9 ed: Lippincott Williams & Wilkins.
- Reddy K.R., Mutalik S. and Reddy S., (2003) Once-daily sustained-release matrix tablets of nicorandil: formulation and in vitro evaluation. AAPS PharmSciTech 4, E61.
- Kumar R., Rajarajeshwari N., Swamy V. B. N.,(2012) Isolation and evaluation of Borassus flabellifer mucilage as a natural suspending agent. International Journal of PharmTech Research;4(4):1614–1630.
- Nussinovitch A., (2009) Major Plant Exudates of the World. In Plant Gum Exudates of the World: CRC Press.
- Sheth NS, Shah NV and Shah NC,(2010). Extraction of mucilage from Occimum americanum Linn and its role as disintegrant in tablets formulation. J. Global Pharma Tech. 2(12): 26-31.
- Harborne, J.B., (1998) Sugars and their derivatives inPhytochemical methods: A guide to modern techniques of plant analysis. 3rd ed. London: Chapman & Hall, pp: 235-90.
7. Kokate, C.K., A.P. Purohit and S.B. Gokhale,(2003) Pharmacognosy. 24th ed.Pune: NiraliPrakashan
8. Indian Pharmacopoeia, (1996) 4 ed. Ministry of healthand family welfare, Govt. of India, New Delhi;Controller of publications;.A-54.
9. Lala, P.K., (1981) Practical Pharmacognosy. Calcutta, LinaGuha, pp: 135.
10. Bal, T., P.N. Murthy and S. Sengupta, (2012). Isolation and analytical studies of mucilage obtained from the seed of Dilleniaindica(family dilleniaceae) by use of various analytical techniques. Asian Journal of Pharmaceutical and Clinical Research, 5(3):65-67.
11. Pabon, C.V., P. Frutos, J th .L. Lastres and G. Frutos,(1992). In-vitro study of mixed controlled releasematrix tablets containing HPMC and polyamide. Drug Development and Industrial Pharmacy,18(20): 2163-71.
12. Malviya, R., (2011). Extraction and characterization of selected mucilage as a pharmaceutical excipients. Polim Med, 41(3): 39-44.
13. Singh, S., Bothara, S. B., (2014)Physico-chemical and structural characterization of mucilage isolated from seeds of Diospyros Melonoxylon Roxb., Brazilian Journal of Pharmaceutical Sciences, vol(50),n(4).
14. Malviya, R., P. Srivastava, M. Bansal and P.K. Sharma, (2010).Mango Peel Pectin as Super disintegrating Agents. Journal of Scientific and Industrial Research, 69: 688-90.
15. Fouad H.Kamel, Aza Ismail Abdi, Salwa H.Kamel, Sarkate Hamd Ali, (2016). Effect of diagnosis X-rays on oral bacterial survival and their sensitivity to some antibiotics. International Journal of Advanced Research, Volume (4), Issue (7).
)
