Document Type : Research Paper

Authors

College of Science, University of Anbar

10.37652/juaps.2014.122636

Abstract

The purpose of the present study is to find the impact of benzene and its components on some aspects of physiological parameters in the blood of workers in the filling stations as samples were collected study and synthesized from (60) a sample of the blood of people working in filling stations and in direct contact with gasoline and (60) a sample of the blood of people who do not work in gas stations and considered as a control group. The laboratory tests was conducted and included: blood tests include a Complete Blood Count , WBC , RBC , Hb , PCV , ESR and Plat. count. The results of the study showed the following :The results showed a significant effect at the level of probability (P <0.05) in the Red blood cell count and packed cell volume and platelet count, white blood cells count and (DLC) as neutral , lymphoma ,acidophilic and basophilic as well as in the indicators of red blood cell (MCV, MCHC) in the blood of workers, compared with the control group. Non-significant differences in the values of white blood cell counts erythrocyte sedimentation rate and hemoglubin and monocyte .

Main Subjects

  1. 1.    Lewis, RJ.(1992).  Sax’s Dangerous Properties of Industrial Materials. 8th ed. New York: VanMostrand Reinhold.
  2. 2.    Weast , R. C. , Lide , D. R. Astle , M. J. and Beyer, W. H . (1965 ) . Handbook of Chemistry and Physics, 70th ed. CRC Press , Boca Raton . FL.
  3. 3.     Mackay, D. and Leinonen, P. J. (1975) .  "The Rate of Evaporation of Low Solubility Contaminants from Water Bodies to atmosphere . Environmental Sci. and Technol. 9: 1178-1180 Cal report series 289 , National Toxology Program , Triangle Park , NC. 1986.
  4. 4.    Yaris, F. Dikici, M. Akbulut, T. Yaris, E. and  Sabuncu ,H. (2004) . Story of benzene and leukemia:epidemiologic approach of Muzaffer Aksoy. J. Occup Health.;46(3):244-247.
  5. 5.    Lan, Q. Zhang, L. Li, G. Vermeulen, R. Weinberg, RS. Dosemeci, M. Rappaport, SM. Shen, M. Alter, BP. Wu, Y. Kopp W, Waidyanatha S, Rabkin C, Guo W, Chanock S, Hayes RB, Linet M, Kim S, Yin S, Rothman N. and Smith M . (2004) . Hematotoxicity in workers exposed to low levels of benzene. Science;306:1774–6.
  6. 6.    Hayes RB, Songnian Y, Dosemeci M and  Linet M.( 2001 ) . Benzene and lymphohematopoietic malignancies in humans. Am. J. Ind. Med.;40(2):117-126.
  7. 7.    Rothman, N. Smith, MT. Hayes, RB. Li, GL. Irons, RD. Dosemeci ,M. Haas, R. Stillman, WS. Linet, M. Xi, LQ. Bechtold, WE. Wiemels , J. Campleman, S. Zhang, L. Quintana, PJ. Titenko-Holland, N.Wang, YZ. Lu ,W. Kolachana ,P. Meyer, KB.and Yin, S. (1996) . An epidemiologic study of early biologic effects of benzene in Chinese workers. Environ Health Perspect.;104(Suppl 6):1365-1370.
  8. 8.    Ward, C.O. kuna,  R.A. Snyder, N.K.  Alsaker, R.D. Coate, W.B. and  Craig, P.H. (1985).  Sub-chronic inhalation toxicity of benzene in rats and mice. Am. J. Ind. med. 7 (5-6) 457-473.
  9. 9.    Qu , Q. Shore, R. Li, G. Jin, X. Chen , LC. Cohen, B. Melikian, AA. Eastmond , D. Rappaport, SM, Yin ,S. Li, H. Waidyanatha , S. Li Y, Mu, R. Zhang ,X.and  Li, K.  ( 2002 ) . Hematological changes among Chinese workers with a broad range of benzene exposures. Am. J. Ind. Med.;42:275–285.

10. Li, G. and Yin, S.(2006) . Progress of epidemiological and molecular epidemiological studies on benzene in China. Ann. NY Acad .Sci.; 1076:800-9. [PubMed: 17119257] .

11. Snyder, R. and Hedli, CC. (1996) . An overview of benzene metabolism. Env Health Perspect.;104;1165-1171.

12. Wiester, J. Darrell ,W. Winsett. Judy, H. Donald , L. and Daniel L Costa . ( 2002) . Partitioning of benzene in blood: influence of hemoglobin type in humans and animals. Environ Health Perspect; 110(3): 255–261.

13. Löwenberg, B. Downing , JR.and  Burnett, A. (1999) . Acute myeloid leukemia. N Engl J Med.;341(14):1051-1062.

14. Abdel Aziz,I .   Salam, z. and  Ossama, A . (2006) . Hematological and Biochemical Studies for Gasoline Toxicity Among Gasoline Workers In Gaza Strip . Hematological And Biochemical Studies .

15. Cronkite. E.P.  Drew. R.T,  lnoue. T., Hirabayashi. Y. and  J.E. Bullis. (1989). Hematotoxocity and carcinogenicity of inhaled benzene. Environ. Health perspect. 82 97-108.

16. Ward, E. Horning, R. Morris, J. Rinsky, R. Wild, D. Halperin, W. (1996).  Risk of low red or white blood cell count related to estimated benzene exposure in a rubber worker cohort (1940-1975). Am. J. Ind. Med. 29 (3) 247-257.

17. Bazzaz, A. A.; Muhsin, S. S. and Sulaiman, N. M. (1989). Haematological changes in blood of mice induced by subchronic ingestion of lead monoxide. Biol. Sci. Res., 20 (1): 31-40.

Dacie , S.J.V and Lewis , S.M . (1995) . Practical Haematology .8 th ed . Churchill Livingston Inc ., New York